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Multiparametric Assessment to Investigate Prognostic Factors for Disease Evolution a nd Evolutionary Patterns of Cognitive Status in RRMS

RECRUITINGN/ASponsored by University Hospital of Mont-Godinne
Actively Recruiting
PhaseN/A
SponsorUniversity Hospital of Mont-Godinne
Started2022-06-06
Est. completion2026-06-06
Eligibility
Age18 Years – 50 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05510817

Summary

This prospective study combining non conventional MRI techniques, neuropsychological screening tools, and a neurophysiological work-up using a sensitive and validated battery, will evaluate the predictive value of these measures and will explore the changes of the cognitive scores from baseline.

Eligibility

Age: 18 Years – 50 YearsHealthy volunteers accepted
Inclusion Criteria:

* active MS, according to the Lublin criteria
* disease duration \< 10 years before initiating or changing a disease-modifying therapies,
* relapse- and steroid-free for at least 1 month before MRI acquisition
* between 18-50 years old
* having given informed consent
* with no significant comorbidity other than MS or substance abuse that could interfere with cognitive performances

Exclusion Criteria:

* progressive forms of MS

Conditions2

Multiple SclerosisMultiple Sclerosis, Relapsing-Remitting

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