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PREOPANC-4 Implementation Program for Locally Advanced Pancreatic Cancer

RECRUITINGSponsored by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Actively Recruiting
SponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Started2021-07-01
Est. completion2024-12-31
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05524090

Summary

A prospective, nationwide, implementation program of the international standard of excellence for locally advanced pancreatic cancer (LAPC) care in the Netherlands (2021\[7\]-2030\[6\]), including a multidisciplinary training program by the four leading international expert centers. The PREOPANC-4 project aims a safe and patient-centered implementation of the international standards of excellence for LAPC (surgery) in the Netherlands.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Age 18 years or older
* Pathology-confirmed (LAPC)\*
* CT-based non-progressive disease (RECIST criteria) after at least 4 months of systemic chemotherapy (\[m\]FOLFIRINOX / gemcitabine-nab-paclitaxel).

Exclusion Criteria:

* Metastatic pancreatic cancer prior to induction chemotherapy.

  * According to the Dutch Pancreatic Cancer Group (DPCG) definition: \>90 degrees arterial tumor involvement (i.e. superior mesenteric artery, celiac axis, and/or hepatic artery) and/or portovenous involvement of either \>270 degrees or occlusion.

Conditions5

CancerChemotherapy EffectLocally Advanced Pancreatic AdenocarcinomaPancreatic Adenocarcinoma Non-resectablePancreatic Cancer

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