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Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health

RECRUITINGN/ASponsored by University of Florida
Actively Recruiting
PhaseN/A
SponsorUniversity of Florida
Started2023-08-30
Est. completion2026-12
Eligibility
Age50 Years – 65 Years
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT05541887

Summary

Previous studies have shown that polyphenol-rich foods can positively affect cognitive functions, memory, and mood in humans. We hypothesize that both acute and chronic intake of muscadine wine polyphenols will improve cognitive performance and mood through regulating the HPA axis, alleviating inflammation and oxidative stress, and/or inhibiting monoamine oxidase activities

Eligibility

Age: 50 Years – 65 YearsHealthy volunteers accepted
Inclusion Criteria:

* Healthy
* BMI (18.5-29.9)
* Body weight ≥110 pounds

Exclusion Criteria:

* Pregnancy
* Breast-feeding
* Smokers
* Diabetic
* Heavy drinkers
* Subjective but not clinically diagnosed cognitive impairment (Montreal cognitive assessment score \<26),
* Inability to understand the cognitive function tasks
* Intake of medication that might influence the outcome of the study (e.g. psychostimulant)
* cannabis product user
* Clinically diagnosed mental illnesses
* Cardiovascular and neurological disorders
* Uncontrolled hypertension

Conditions4

AnxietyCognitive PerformanceMemoryMood

Locations1 site

Food Science and human nutrition department at University of Florida
Gainesville, Florida, 32611
Kylee Mai479-203-8170cmai1@ufl.edu

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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