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Clinical and Diagnostic Features of Endocarditis

RECRUITINGSponsored by University Hospital of Ferrara
Actively Recruiting
SponsorUniversity Hospital of Ferrara
Started2022-09-09
Est. completion2025-09-30
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

The burden of endocarditis has changed in the last years due to an increase in percutaneous valve procedures offered to a more fragile, and old population. Therefore an update in epidemiology data is necessary. The Observational prospective multicenter study to characterize the cLinical ANd DiagnoStiC feAtures of endocarditis in the contemPorary Era, (ENDO-LANDSCAPE study) is an observational, multicenter and international study. The study has two arms: retrospective and prospective. The retrospective arm will involve collecting data from patients discharged with a diagnosis of endocarditis between 2016 and 2022. The data obtained in the retrospective arm of the study will be utilized in a power calculation to determine the sample size for the prospective arm of the study. In the prospective phase in every participating center, all patients referred for echocardiography to assess for endocarditis and those with established endocarditis independent of the screened request will be eligible. Patients will then be stratified according to the presence or abscence of endocarditis. Those with an established diagnosis of endocarditis will be prospectively followed for outcomes.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Patients above the age of 18 years.
* all consecutive patients referred for echocardiography (transthoracic or transesophageal approach) to exclude endocarditis.
* patients with a diagnosis of endocarditis on echocardiography independently by the request for the exam.

Exclusion Criteria:

* patient's refusal.

Conditions2

EndocarditisHeart Disease

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