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Utility of PET-MRI in Surveillance of Paediatric Brain Tumours

RECRUITINGN/ASponsored by Sheffield Children's NHS Foundation Trust
Actively Recruiting
PhaseN/A
SponsorSheffield Children's NHS Foundation Trust
Started2024-02-28
Est. completion2025-03
Eligibility
Age8 Years – 18 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05553899

Summary

This is a pilot project to explore the utility of PET-MRI in the post-treatment surveillance of high-grade gliomas or medulloblastomas in children in our institution.

Eligibility

Age: 8 Years – 18 YearsHealthy volunteers accepted
Inclusion Criteria:

* Have a presumptive or histologically confirmed diagnosis of a malignant brain tumour requiring treatment
* Diagnostic uncertainty about tumour recurrence post-treatment based on conventional MR imaging in the opinion of the MDT
* Have a life expectancy of at least three months
* Able to comply with an MRI scan without a general anaesthetic

Exclusion Criteria:

* Unable to comply with an MRI scan without a general anaesthetic
* Diabetes or other causes of hyperglycaemia
* Pregnancy
* Patient body habitus above scanner dimensions
* Standard contra-indication to MRI (eg. pacemaker, non-compatible metallic implants, altered renal function)

Conditions2

Brain Tumor, PediatricCancer

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