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Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline

RECRUITINGSponsored by Johns Hopkins University
Actively Recruiting
SponsorJohns Hopkins University
Started2022-04-01
Est. completion2027-04-01
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT05556395

Summary

The goal of this study is to gain a better understanding of why some individuals who have suffered a stroke experience post-stroke cognitive decline. Specifically this study is testing whether global disruption of the blood-brain barrier detected at the time of the stroke is informative about the risk of post-stroke cognitive decline over the next 3 years.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Acute ischemic stroke demonstrated on an MRI scan that includes perfusion imaging with an exogenous contrast agent

Exclusion Criteria:

* Inability to perform telephone-based cognitive assessments

Conditions2

Alzheimer's DiseaseIschemic Stroke

Locations1 site

Johns Hopkins Hospital
Baltimore, Maryland, 21287
Diane Echavarria410-502-5355dechava1@jhu.edu

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