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Risk Model of Cognitive Impairment in Diabetes

RECRUITINGSponsored by The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Actively Recruiting
SponsorThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Started2022-09-01
Est. completion2024-12-31
Eligibility
Age40 Years – 80 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05590442

Summary

Development and validation of a risk model for predicting the risk of mild cognitive impairment among individuals of type 2 diabetes.

Eligibility

Age: 40 Years – 80 YearsHealthy volunteers accepted
Inclusion Criteria:

* Patients with type 2 diabetes mellitus ;
* Aged:40 -80 years ;
* Montreal Cognitive Assessment Scale (MoCA) scores 19 - 30;

Exclusion Criteria:

* Mini-mental State Examination(MMSE) scores \< 24;
* Other dementia related neurological diseases or depression, schizophrenia in the past 2 years;
* Central nervous system diseases, including brain trauma, intracranial hemorrhage, acute cerebral infarction;
* Severe sinusitis, nasal cavity and sinus polyps, skull base or nasopharyngeal tumors and other space occupying lesions, congenital diseases and traumatic history of nose, maxillofacial and skull base affecting olfaction;
* Diabetic acute and chronic complications, including diabetic ketoacidosis, a hyperglycemic hyperosmolar state or severe hypoglycemic coma.

Conditions3

DiabetesMild Cognitive ImpairmentType 2 Diabetes Mellitus

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