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Risk Model of Cognitive Impairment in Diabetes

NOT_RECRUITINGSponsored by The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
No longer actively recruiting
SponsorThe Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Started2022-09-01
Est. completion2024-12-31
Eligibility
Age40 Years – 80 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05590442

Summary

Development and validation of a risk model for predicting the risk of mild cognitive impairment among individuals of type 2 diabetes.

Eligibility

Age: 40 Years – 80 YearsHealthy volunteers accepted
Inclusion Criteria:

* Patients with type 2 diabetes mellitus ;
* Aged:40 -80 years ;
* Montreal Cognitive Assessment Scale (MoCA) scores 19 - 30;

Exclusion Criteria:

* Mini-mental State Examination(MMSE) scores \< 24;
* Other dementia related neurological diseases or depression, schizophrenia in the past 2 years;
* Central nervous system diseases, including brain trauma, intracranial hemorrhage, acute cerebral infarction;
* Severe sinusitis, nasal cavity and sinus polyps, skull base or nasopharyngeal tumors and other space occupying lesions, congenital diseases and traumatic history of nose, maxillofacial and skull base affecting olfaction;
* Diabetic acute and chronic complications, including diabetic ketoacidosis, a hyperglycemic hyperosmolar state or severe hypoglycemic coma.

Conditions3

DiabetesMild Cognitive ImpairmentType 2 Diabetes Mellitus

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