Iodine Uptake After a Low Iodine Diet

Summary

The goal of this clinical trial is to compare the difference in thyroid uptake of a low dose radioactive iodine (10 MBq 123-I or 37 MBq 123-I) in athyreotic patients with differentiated thyroid carcinoma before and after a low iodine diet (LID) of 7 days. The main question it aims to answer is: • What is the difference in iodine uptake before and after a LID of 7 days? Uptake of a low dose of 123-iodine will be measured in participants before and after a low iodine diet of 7 days. Researchers will compare the uptake (%) before and after the LID.

Eligibility

Inclusion Criteria:

* Patients, men and women above the age of 18 years, have to be diagnosed with DTC and have to follow a LID prior to the 131I ablation therapy according to the Dutch DTC guideline
* Patients have to be fit to adhere to the study protocol
* Patients have to be able to read and understand the Dutch language

Exclusion Criteria:

* Age \< 18 years
* Patients using amiodarone
* Patients receiving iodinated contrast \< 3 months before the LID
* Pregnancy
* Patients prepared for ablation therapy with rhTSH
* Renal impairment, EGFR \<30ml/min/1,73m2

Conditions2

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