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Complementary Investigation of Perfusion and Anatomy Measures of the Heart With MRI and Combined PET/MRI

RECRUITINGSponsored by University of Zurich
Actively Recruiting
SponsorUniversity of Zurich
Started2022-11-21
Est. completion2026-04-01
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05609214

Summary

The goal of this observational study is to evaluate the complimentary information of anatomy, perfusion and viability of PET and MR. The main question\[s\] it aims to answer are: * to compare perfusion and anatomy measurements and perfusion related signals from PET and MR imaging and estimate its prognostic values. * to evaluate potential optimization of routine scanning procedure with regards to completeness and potential added value of quantitative measurements.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Male and Female participants over the age of 18 years
* Written informed consent by the participant after information about the research project
* Symptoms consistent with possible coronary artery disease
* Clinical referral for a vasodilator stress CMR and/or PET examination

Exclusion Criteria:

* Patients with high degree heart block
* Contraindications to gadolinium-enhanced CMR examination
* Severe claustrophobia
* Specific implantable devices which are contraindicated for CMR
* Current pregnancy
* Advanced renal disease (GFR\<30)
* Uncontrolled obstructive pulmonary disease or asthma
* Atrial fibrillation at the time of study enrolment

Conditions2

Coronary Artery DiseaseHeart Disease

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