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Evaluation of the Use of the FUR to Quantify Tumor Glucose Consumption in Oncologic PET

RECRUITINGSponsored by Academisch Ziekenhuis Maastricht
Actively Recruiting
SponsorAcademisch Ziekenhuis Maastricht
Started2024-01-15
Est. completion2025-04-01
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

The goal of this study is to evaluate the use of new method to quantify the amount of sugar a tumor consumes using PET/CT. The main questions it aims to answer are: * Is the new quantification method superior with respect to the method currently used in the clinic? * Does the new quantification method provide accurate assessment of the sugar consumption of tumours? Participants who will undergo a standard care FDG PET/CT scan will in additional receive a dynamic PET/CT scan prior to the standard care scan. In addition blood samples will be drawn at three time points during the examination.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Patients who receive an 18F FDG PET/CT scan as part of standard care
* Be competent and be 18 years of age or older

Exclusion Criteria:

* Diabetes (fasted blood glucose \> 7 mmol/L)
* Not fasted \> 4 hours
* Physical exercise within 24 hours
* Earlier treatment for carcinoma with radio/chemo-therapy
* Active inflammation (fever \> 38 degrees, CRP \> 5)
* Any condition or medical indication (such as claustrophobia) that indicates that the patient will not be able to lie still for the duration of the dynamic PET/CT examination
* Pregnant or breast feeding

Conditions3

CancerLung CancerLymphoma

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