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AIO-BNHO Comprehensive Clinico-genomics Database Network - AIO-BNHO CONNECT

RECRUITINGSponsored by AIO-Studien-gGmbH
Actively Recruiting
SponsorAIO-Studien-gGmbH
Started2022-12-08
Est. completion2025-12
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05701150

Summary

National, retro- and prospective, observational, multicenter clinical research platform to connect clinical and genomic data of patients with advanced (locally advanced, inoperable, or metastatic) solid tumors (excluding NSCLC, SCLC, and mesothelioma) with results from multi-gene next-generation sequencing (NGS) panels (\>30 genes)

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Diagnosis of advanced (i.e., locally advanced, inoperable, or metastatic) solid tumor, ineligible for curative surgery and/or curative systemic therapy
* Available results of commercial or non-commercial RNA- and/or DNA-based multi-gene NGS panels with \>30 genes analyzed; for non-commercial panels a list of all tested genes and multiple gene biomarkers (e.g., tumor mutational burden (TMB), microsatellite status) must be provided
* Age ≥ 18 years
* Signed and dated informed consent form (not applicable for inclusion of deceased patients)

Exclusion Criteria:

* Diagnosis of NSCLC/SCLC (C34) or mesothelioma (C45)
* NGS results older than two years at the date of patient inclusion

Conditions2

Advanced Solid TumorCancer

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