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Familial Pancreatic Cancer PROPHilation Program in Italy

RECRUITINGN/ASponsored by Associazione Italiana per lo Studio del Pancreas
Actively Recruiting
PhaseN/A
SponsorAssociazione Italiana per lo Studio del Pancreas
Started2022-12-20
Est. completion2027-12-20
Eligibility
Age18 Years – 80 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05724992

Summary

The goal of the PROPH-ITA Study is to perform genetic testing in family members of pancreatic cancer patients who may have a genetic predisposition. The subjects belong to the Italian Registry of Families At Risk of Pancreatic Cancer (IRFARPC, #NCT04095195). This investigational study will assess the genetic background of subjects with familiarity with pancreatic cancer only. Participants may accept to undergo genetic testing as part of the IRFARPC registry, through a saliva-swab-based 41-gene panel test. Up to 3,000 participants will be enrolled in this study.

Eligibility

Age: 18 Years – 80 YearsHealthy volunteers accepted
Inclusion Criteria:

* Being enrolled on the IRFARPC registry
* Having familiarity for pancreatic cancer (according to the IRFARPC criteria, Capurso et al. Dig Liv Dis, 2020)
* Willingness to participate in saliva-swab-based genetic testing

Exclusion Criteria:

\- Already known genetic mutation

Conditions2

CancerCandidates for Hereditary Pancreatic Cancer Testing

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