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Genetic Predisposition Testing Program for Pancreatic Neuroendocrine Neoplasms

RECRUITINGSponsored by University of California, San Francisco
Actively Recruiting
SponsorUniversity of California, San Francisco
Started2023-04-07
Est. completion2026-12-31
Eligibility
Age18 Years+
Locations3 sites
View on ClinicalTrials.gov →

NCT05746182

Summary

This is a prospective observational multi-center pilot study of germline testing for participants receiving care at University of California participating locations with a new or existing diagnosis of Pancreatic Neuroendocrine Neoplasms (PanNEN). This protocol is an extension of existing Genetic Testing Station efforts at University of California, San Francisco (UCSF)

Eligibility

Age: 18 Years+
Inclusion Criteria:

1. Histologically confirmed PanNEN.

   a. The diagnostic biopsy may have been taken from any site (primary or metastatic).
2. New and existing PanNEN participants will be eligible (any grade, any stage, any age \> 18 years).
3. Participants willing and able to comply with the study procedures.

Exclusion Criteria:

1. Inability to provide informed consent.
2. For participants who have not had prior testing with a dedicated germline pane of at least 80 genes:

   1. Inability to speak/read a language supported by the germline testing station (GTS). The supported languages currently include English, Korean, Japanese, Vietnamese, Russian, Tagalog, Farsi, Spanish, Cantonese, Mandarin, and Arabic).
   2. Active hematologic malignancy.
   3. History of allogenic bone marrow transplant or stem cell transplant.

Conditions2

CancerPancreatic Neuroendocrine Neoplasm

Locations3 sites

University of California, Los Angeles
Los Angeles, California, 90095
Randy Hecht, MD
Univeristy of California, San Diego
San Diego, California, 92093
Paul Fanta, MD
University of California, San Francisco
San Francisco, California, 94143
Bryan Le415-502-6313bryankhuong.le@ucsf.edu

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