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Characterization of Circulating and Tumor-infiltrating Immune Cells in Malignant Brain Tumors

RECRUITINGSponsored by Pietro Mortini, MD, Prof.
Actively Recruiting
SponsorPietro Mortini, MD, Prof.
Started2022-08-01
Est. completion2028-07-31
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05831631

Summary

The goal of this observational study is to characterize the circulating leukocyte profile and the immune T cells distribution within the tumor in patients with malignant brain tumors and to correlate these findings with the oncological outcome. Participants will be subjected to blood sampling before surgery and for 12 months of follow-up. Additional sampling and analysis will be performed on tumor samples.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion criteria:

* Adult patients (≥18 years)
* Able to express informed consent
* With primary or secondary malignant brain tumor
* Requiring neurosurgical treatment (radiosurgery, stereotactic biopsy, surgery)

Exclusion Criteria:

* Patients who do not meet inclusion criteria.

Conditions3

Brain Tumor - MetastaticBrain Tumor, PrimaryCancer

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