Investigating Cognitive Impairment in Young Patients With Cancer Prospectively

Summary

The MyBrain study investigates the brain function of children, adolescents and young adults during and after chemo treatment for cancer. The tests include 1) cognitive skills such as memory and attention; 2) the brain's electrical activity; 3) and biological markers related to brain function. The aim of the study is to better understand the trajectories of cognitive functioning and measures that have been associated with cognitive impairment in patients treated with chemotherapy.

Eligibility

Inclusion Criteria:

* Patients who are newly diagnosed with a non-CNS cancer and will undergo chemotherapy at University Hospital Copenhagen, Rigshospitalet.
* At the age of 7-29 years at diagnosis
* Each patient is matched (1:1) with a control participant within 24 months of age. The controls are recruited from the patient's own social circle and can be a friend, partner, or close family (sibling or cousin).

Exclusion Criteria:

* Unable to speak and understand Danish
* Severe intellectual disability or mental health disorder that hinders participation
* Brain metastases,
* Terminal illness
* Have had a previous chemotherapy or radiotherapy treatment

Conditions10

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