Acute Cardiac Dysfunction in Critical Illnes

Summary

The overall aim of the study is to establish the clinical importance of cardiac dysfunction, by estimating its incidence and impact on short- and long-term outcomes, in a mixed population of critically ill patients with multi-organ failure. Pathogenesis of cardiac dysfunction in critical illness and key molecules linked to this will be explored.

Eligibility

Inclusion Criteria:

1. Patients aged \> 18 years
2. Admitted to a participating ICU within 24 hours
3. Significant organ dysfunction involving at least two organ systems. This is defined as fulfilling both of the following:

   * At least 4 points on the SOFA scale (Sequential Organ Failure Assessment scale)
   * Having at least 1 point on the SOFA scale from at least two organ systems
4. Given informed consent from patient or permission to participate from next of kin

Exclusion Criteria:

1. Echocardiographic examination not possible (e.g., pneumothorax, draping etc) or very low echocardiographic examination quality
2. Not being examined with echocardiography within 24 hours from inclusion
3. Retracted consent to participate

Conditions7

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