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Ultra-Low Contrast Angiography in AKI

RECRUITINGPhase 3Sponsored by Tulane University
Actively Recruiting
PhasePhase 3
SponsorTulane University
Started2025-09-05
Est. completion2026-12
Eligibility
Age18 Years – 100 Years
Healthy vol.Accepted
Locations2 sites

Summary

The aim of this study is to evaluate the safety of ultra-low contrast coronary angiography in patients with pre-existing acute kidney injury.

Eligibility

Age: 18 Years – 100 YearsHealthy volunteers accepted
Inclusion Criteria:

* Hospitalized patients who have AKI at admission or who develop AKI during admission and require invasive coronary angiography will be included in the trial.

Exclusion Criteria:

* Stabilized renal function manifested by unchanged or downtrending serum creatinine during a 24-hour period prior to enrollment.
* Contraindication for invasive coronary angiography other than AKI.
* Percutaneous coronary intervention is indicated and cannot be postponed by 7 days.
* Need for renal replacement therapy before coronary angiography or planned renal replacement therapy after coronary angiography (if premeditated before coronary angiography).
* Administration of intravascular contrast media during 7 days prior to the coronary angiography or within 6 days after coronary angiography.
* Pregnant patients, prisoners, cognitively impaired subjects, age below 18 years, unable or unwilling to provide informed consent.

Conditions2

Acute Kidney InjuryHeart Disease

Locations2 sites

Tulane University Medical Center
New Orleans, Louisiana, 70112
Zach Rozenbaum, MD504-988-5493zrozenbaum@tulane.edu
University Medical Center
New Orleans, Louisiana, 70112
Zach Rozenbaum, MD504-988-5493zrozenbaum@tulane.edu

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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