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Record Voxel Rate Nonlinear Optical Microscope to Unravel Brain Connectome and Signaling

RECRUITINGSponsored by National Taiwan University Hospital
Actively Recruiting
SponsorNational Taiwan University Hospital
Started2023-05-01
Est. completion2026-12-31
Eligibility
Age20 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05943262

Summary

The research aims to develop a novel pathological technology, including rapid whole-mount tissue H\&E \& IHC staining protocol and high-resolution nonlinear optical microscopy imaging system, to intraoperatively assess brain tumor grade, types and other biological parameters.

Eligibility

Age: 20 Years+Healthy volunteers accepted
Inclusion Criteria:

1\. Patients older than the age of 20 with diagnosis of brain tumor (both newly-diagnosed or recurrent) who are suitable and willing to receive resection surgery.

Exclusion Criteria:

1. Patients who cannot give consent to participate in the study.
2. The tumor samples failed to give a conclusive pathological diagnosis by standard pathological workflow.
3. Patients who only receives biopsy surgery rather than resection surgery.
4. Significant post-irradiation effect or radiation necrosis reported in the pathological examination.

Conditions3

Brain CancerBrain TumorCancer

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