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IVIM & OLINK in Sarcoma

RECRUITINGPhase 2Sponsored by University Health Network, Toronto
Actively Recruiting
PhasePhase 2
SponsorUniversity Health Network, Toronto
Started2024-03-05
Est. completion2026-11-30
Eligibility
Age18 Years – 100 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05950594

Summary

The hypoxia \> metastasis axis suggests that a DWI-based biomarker of hypoxia incorporating IVIM may be able to predict metastasis in STS patients, ultimately enabling stratification for personalized treatments at the time of diagnostic (MR) imaging, without adding an excessive burden to the patient or clinical workflow (typical DWI/IVIM sequences can be acquired acquired in approximately 5 minutes).

Eligibility

Age: 18 Years – 100 YearsHealthy volunteers accepted
Inclusion Criteria:

* Age ≥ 18 years
* Ability to understand and the willingness to sign a written informed consent document
* Grade 2 or 3 soft tissue sarcoma greater than 5 cm in largest dimension

Exclusion Criteria:

* Contraindication to MRI scan as per current institutional guidelines (for patients requiring MRI)

Conditions2

CancerSoft Tissue Sarcoma

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