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Influence of Autonomy on Motor Learning in People With Parkinson's Disease

RECRUITINGN/ASponsored by National Taiwan University Hospital
Actively Recruiting
PhaseN/A
SponsorNational Taiwan University Hospital
Started2023-08-21
Est. completion2025-07-31
Eligibility
Age20 Years+
Healthy vol.Accepted

Summary

The goal of this clinical trial is to explore the benefits of autonomy supported learning in patients with Parkinson's disease. The main questions to answer are: * Whether autonomy supported learning can benefit motor learning in PD patients * Whether autonomy supported learning can enhance intrinsic motivation and/ or information processing of PD patients in learning a new task. * Whether autonomy supported learning can facilitate cortical excitability change after practicing a new task. Participants will be recruited into two groups (Self-control group, SC; and yoked group, YK) to learn a finger-pressing trajectory matching task * Participants in SC group will have choice over feedback schedule during trial practice * Participants in YK group will receive feedback with no-choice during trial practice Researchers will compare the retention test performance to see if autonomy supported learning will lead to better learning effect.

Eligibility

Age: 20 Years+Healthy volunteers accepted
Inclusion Criteria:

* age above 20-years-old
* able to follow instructions to perform the tasks (Montreal Cognitive Assessment ≥ 24)
* no surgery and injury in upper extremities in recent 6 months

Exclusion Criteria:

* other neurological disorders in addition to Parkinson's disease
* Parkinson's disease dementia
* symptom of severe tremor in upper extremities (score ≥ 3 in Question 15 to 18 of UPDRS-III)
* deep brain stimulation or pacemaker implanted
* medical history of seizure
* a blood-relative with history of epilepsy
* unstable medical conditions
* pregnancy

Conditions2

Parkinson DiseaseParkinson's Disease

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