Evolution of PET Fixation With FDG at the End of Antibiotic Treatment of Infective Endocarditis on Valvular Prosthesis

Summary

In patients with prosthetic valve endocarditis (PVE) and pathological valvular FDG uptake on the initial FDG-PET and not referred to valve replacement at the acute phase, the study will assess whether FDG-PET is able to identify those at increased risk of PVE relapse.

Eligibility

"Inclusion criteria:

* Patient aged 18 or over;
* Have a prosthetic valve implanted surgically or by catheter for at least 3 months;
* Presenting a definite IE on a prosthetic valve (ESC definition in force);
* Having benefited from an FDG-PET examination for diagnostic purposes as part of the treatment revealing pathological hyperuptake at the level of the prosthetic valve AND carried out \<15 days after the start of antibiotic therapy for infective endocarditis;
* Absence of cardiac surgical intervention performed for the current episode of AE or planned before the end-of-treatment FDG-PET

Exclusion criteria:

* Patient under legal protection, guardianship or curators;
* Pregnancy, breastfeeding;
* Patient not affiliated to a health insurance scheme or not a beneficiary of a social security scheme;
* Simultaneous participation in a study on FDG-PET;
* Absence of informed consent signed by the patient."

Conditions2

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