|

Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion

RECRUITINGN/ASponsored by Shengjing Hospital
Actively Recruiting
PhaseN/A
SponsorShengjing Hospital
Started2017-01-01
Est. completion2026-07-01
Eligibility
Age18 Years – 80 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT05990244

Summary

this study will investigate the relationship between tumor stiffness and adhesion in gliomas using MRE. By utilizing preoperative MRE and Intraoperative neuronavigation, followed by comprehensive molecular pathology analysis, we aim to explore the correlation of tumor stiffness and adhesion with molecular and genetic characteristics of gliomas. Additionally, the predictive value of MRE in terms of pathological staging and prognosis will be determined. This research may pave the way for improved clinical decision-making, personalized treatment approaches, and more accurate clinical trials for glioma patients.

Eligibility

Age: 18 Years – 80 YearsHealthy volunteers accepted
Inclusion Criteria:

1. age older than 18 years
2. Karnofsky performance status higher than 60
3. with written informed consent
4. MRE performed within one week before surgery
5. tumor diameter \> 2 cm

Exclusion Criteria:

1. previous treatment for glioma
2. inability to complete MRE due to intolerance (e.g., vibration-related discomfort or claustrophobia)
3. completed MRE with suboptimal wave image quality (e.g., motion artifacts or inad-equate wave amplitude)
4. failure to proceed with surgery after MRE
5. missing IDH results

Conditions2

CancerGlioma

Browse More Trials

Cancer trials

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.