|

Parathyroid Tumor Clonal Status

RECRUITINGSponsored by Washington University School of Medicine
Actively Recruiting
SponsorWashington University School of Medicine
Started2023-07-28
Est. completion2031-01-31
Eligibility
Age18 Years – 80 Years
SexFEMALE
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT05997810

Summary

To define the frequency of monoclonal-X and polyclonal-X tumors in hyperparathyroid disorders patients having PTX and to define the relationship between parathyroid tumor clonal status and multiple gland neoplasia (MGN), we will compare surgical and pathologic outcomes to tumor clonal status in a multicenter cohort of patients having bilateral neck exploration (BNE) and PTX (primary objectives).

Eligibility

Age: 18 Years – 80 YearsSex: FEMALEHealthy volunteers accepted
Inclusion Criteria:

* 1\. Diagnosed with hyperparathyroidism (primary, secondary, or tertiary), biochemically confirmed (e.g., serum calcium and/or intact PTH consistent with the underlying etiology), and undergoing clinically indicated management
* Female and male patients
* Age ≥ 18 years
* Ability to understand and willingness to sign an IRB approved written informed consent document (or that of legally authorized representative, if applicable).

Exclusion Criteria:

* Patients with a history of cervicofacial irradiation.
* Patients currently taking lithium or with a history of lithium use.
* Pregnant patients

Conditions5

CancerParathyroid TumorPrimary HyperparathyroidismSecondary Hyperparathyroidism (SHPT)Tertiary Hyperparathyroidism

Locations1 site

Washington University School of Medicine
St Louis, Missouri, 63110
Bryan Bear314-651-9717bearb@wustl.edu

Find trials near these locations

All trials in Missouri

Browse More Trials

Cancer trials

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.