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Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis
RECRUITINGSponsored by IRCCS San Raffaele
Actively Recruiting
SponsorIRCCS San Raffaele
Started2021-09-20
Est. completion2024-09-30
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →
NCT06025903
Summary
The purpose of this project is to study genetic determinants of mitochondrial impairment in primary progressive multiple sclerosis. Specific aims are: 1) identify mitochondrial-related pathways, inherited and somatic mitochondrial DNA mutations associated to primary progressive multiple sclerosis, 2) functionally assess the identified genetic alterations.
Eligibility
Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria: * Patients affected by primary progressive or relapsing remitting multiple sclerosis * Patient able to provide informed consent Exclusion Criteria: * Individuals with \< 18 years * Patients not affected by primary progressive or relapsing remitting multiple sclerosis
Conditions1
Multiple Sclerosis
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Actively Recruiting
SponsorIRCCS San Raffaele
Started2021-09-20
Est. completion2024-09-30
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →
NCT06025903