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Evaluation of the Effect of Liposomal L-Arg and Vit C Integration on Mitochondrial Function in Patients With Heart Failure

RECRUITINGPhase 3Sponsored by Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Actively Recruiting
PhasePhase 3
SponsorFondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Started2023-03-21
Est. completion2024-09-30
Eligibility
Age18 Years – 70 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06044194

Summary

Pilot study to assess the effect of L-Arg and Vit C liposomal supplementation on mitochondrial function in patients with heart failure, through analysis of the viability of mitochondria isolated from peripheral blood of mononucleate cells (PBMC).

Eligibility

Age: 18 Years – 70 YearsHealthy volunteers accepted
Inclusion Criteria:

* Age ≥18 years
* Diagnosis of heart failure with preserved EF 45%.

Exclusion Criteria:

* Age \<18 years
* Left ventricular ejection fraction \<45%
* Valvular heart disease
* Previous myocardial infarction or coronary heart disease
* Hypertension
* Diabetes mellitus
* Intolerance to L-arginine and liposomal vitamin C
* Pregnancy
* Lactation.

Conditions2

Heart DiseaseHeart Failure

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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