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An Organoid-based Functional Precision Medicine Trial in Osteosarcoma

RECRUITINGSponsored by Jonsson Comprehensive Cancer Center
Actively Recruiting
SponsorJonsson Comprehensive Cancer Center
Started2024-02-12
Est. completion2027-01-01
Eligibility
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT06064682

Summary

The purpose of this study is to examine if we can predict sensitivity of osteosarcoma to different chemotherapy agents using tissue cultures in the laboratory. We know that different chemotherapy agents can be used in the treatment, but not every sarcoma responds to them equally. It is important to understand if testing of the tissue obtained during a routine biopsy or surgery may be useful in selecting appropriate treatments. In addition, additional testing of the tumor, including genetic testing, will help us to understand osteosarcoma better.

Eligibility

Healthy volunteers accepted
Inclusion / exclusion criteria - Group1:

\- Patients without diagnosis of osteosarcoma and whose imaging studies are suggestive of osteosarcoma and who are planned to undergo biopsy or surgery for diagnostic purposes

Inclusion / exclusion criteria - Group 2:

\- Patients whose imaging studies are suggestive of metastatic osteosarcoma and who are planned to undergo biopsy or surgery for diagnostic purposes

Conditions2

CancerOsteosarcoma

Locations1 site

UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, 90095
Summer Swearingen424-766-9349SSwearingen@mednet.ucla.edu

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