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Innate Immunity in Allergic Asthma

RECRUITINGSponsored by University of Central Florida
Actively Recruiting
SponsorUniversity of Central Florida
Started2021-10-18
Est. completion2025-06
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT06068335

Summary

The purpose of this study is to determine whether a potential type 2 signature, obtained through stimulation of cell lines with various allergens in vitro, correlates with an allergic or asthmatic disease state ex vivo. This type 2 signature will be multi-hierarchical in nature and will be comprised cell surface receptor expression, pathway activation, and gene upregulation.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Participants must be at least 18 years of age
* no history of allergic disease (healthy controls), have clinically diagnosed allergies, or have clinically diagnosed asthma.

Exclusion Criteria:

* Pregnant women and prisoners will be excluded from the study.
* Individuals currently suffering from any acute infections and those known to suffer from light-headedness will be excluded.

Conditions1

Asthma

Locations1 site

University of Central Florida
Orlando, Florida, 32816

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