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tDCS in the Management of Post-COVID Disorders

RECRUITINGPhase 2Sponsored by Universidade Federal de Pernambuco
Actively Recruiting
PhasePhase 2
SponsorUniversidade Federal de Pernambuco
Started2023-08-25
Est. completion2024-07-01
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

Different physical and mental morbidities such as pain, fatigue, depressed mood and cognitive impairment can be triggered by coronavirus infection. Transcranial direct current stimulation (tDCS), an easy-to-apply, non-pharmacological and safe technique, has been used to attenuate these symptoms caused by other diseases, and, therefore, it is expected that it can also attenuate them when generated by COVID-19. It is known that the persistent inflammatory state observed after COVID-19 would be related to the progression of these negative symptoms. As non-invasive brain stimulation can also attenuate acute and persistent inflammation, it can be estimated that tDCS can be a useful tool to recover immune function and reduce post-COVID-19 morbidity.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Long COVID-19 (\>3 months)
* The presence of at least one of the following symptoms, after diagnosed SARS-COV-2 infection:

Persistent pain Fatigue Depressed mood Cognitive impairment

Exclusion Criteria:

* Hemodynamic instability
* Historic of use or abuse of drugs or alcohol
* Use of medications that may interfere with the study results (anti-inflammatories and antibiotics)
* Metallic implant in skull and face
* Implant in the central nervous system
* Pacemaker

Conditions2

DepressionLong COVID

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