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Sex Difference of Coronary Microvascular Dysfunction in Patients With Non-obstructive Coronary Artery Disease

RECRUITINGSponsored by Korea University Anam Hospital
Actively Recruiting
SponsorKorea University Anam Hospital
Started2018-02-01
Est. completion2025-12-31
Eligibility
Age20 Years – 80 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06076551

Summary

Sex difference of coronary microvascular dysfunction evaluated by coronary flow reserve will be assessed in patients with non-obstructive coronary artery disease

Eligibility

Age: 20 Years – 80 YearsHealthy volunteers accepted
Inclusion Criteria:

* Typical/atypical chest pain or ischemic symptoms including dyspnea
* No significant coronary artery stenosis (\<50% stenosis) in coronary angiography or computed tomography

Exclusion Criteria:

* ≥ Moderate valvular heart disease
* Congenital heart disease
* Chronic renal failure (estimated glomerular filtration rate \<30 ml/min/1.73m2) or end-stage renal failure undergoing hemodialysis or peritoneal dialysis
* Asthma, chronic obstructive pulmonary disease and primary pulmonary hypertension
* Receiving anticancer drugs
* Vasculitis associated with autoimmune diseases
* Atrioventricular block with more than second degrees, symptomatic bradycardia, cryo-node failure syndrome, Wolff-Parkinson-White (WPW) patients

Conditions2

Heart DiseaseMicrovascular Angina

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