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Biomarkers in Patients With Suspected HFpEF

RECRUITINGSponsored by NHS Greater Glasgow and Clyde
Actively Recruiting
SponsorNHS Greater Glasgow and Clyde
Started2023-02-02
Est. completion2025-09-29
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06101693

Summary

NT-proBNP does not adequately identify HF(pEF) in people with suspected HF at low levels, particularly in patients with obesity. This study will investigate: 1. alternative cut-offs for NT-proBNP to identify HF(pEF) in people with suspected HF and obesity 2. novel candidate biomarkers to identify HF(pEF) in people with suspected HF and obesity. 3. novel candidate biomarkers to identify HF(pEF) in people with suspected HF and NT-proBNP \<125 ng/L 4. the prevalence of HF in people with suspected HF and low NT-proBNP \<125 ng/L)

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Written informed consent
* Age ≥ 18 years
* NT-proBNP sample taken by primary care physician as part of routine care for suspected heart failure

Exclusion Criteria:

* Unable to consent to inclusion in study due to significant cognitive impairment
* Geographical/ social reasons preventing attending study centre
* Unable to complete study assessments
* Patients presenting with acute HF or a previous diagnosis of HF

Conditions4

Heart DiseaseHeart FailureHeart Failure With Preserved Ejection FractionObesity

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