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Effect of Ketamine on Intraoperative Motor Evoked Potentials

RECRUITINGPhase 3Sponsored by University of California, San Francisco
Actively Recruiting
PhasePhase 3
SponsorUniversity of California, San Francisco
Started2023-12-01
Est. completion2026-12-01
Eligibility
Age18 Years – 100 Years
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT06140927

Summary

The goal of this clinical trial is to learn about the effect of ketamine on intraoperative motor evoked potentials in adult patients undergoing thoracolumbar spinal fusions. Participants will undergo a standard anesthetic. In addition to the standard anesthetic, the patients will be administered increasing doses of ketamine with motor-evoked potentials being measured at each dose, to assess any impacts.

Eligibility

Age: 18 Years – 100 YearsHealthy volunteers accepted
Inclusion Criteria:

* Adult patients (\>18 years of age) undergoing posterior spinal fusions.

Exclusion Criteria:

* Sensitivity or allergy to ketamine.
* Schizophrenia or other psychotic conditions
* Uncontrolled hypertension with systolic blood pressure greater than 180 mmHg
* Myocardial Infarction
* Large vascular aneurysms
* Patients on ketamine as outpatient therapy.

Conditions4

CancerSpinal StenosisSpine FusionSpine Tumor

Locations1 site

University of California, San Francisco
San Francisco, California, 94143
Marc Buren, MD415-514-3781marc.buren@ucsf.edu

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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