Effect of Ketamine on Intraoperative Motor Evoked Potentials

Summary

The goal of this clinical trial is to learn about the effect of ketamine on intraoperative motor evoked potentials in adult patients undergoing thoracolumbar spinal fusions. Participants will undergo a standard anesthetic. In addition to the standard anesthetic, the patients will be administered increasing doses of ketamine with motor-evoked potentials being measured at each dose, to assess any impacts.

Eligibility

Inclusion Criteria:

* Adult patients (\>18 years of age) undergoing posterior spinal fusions.

Exclusion Criteria:

* Sensitivity or allergy to ketamine.
* Schizophrenia or other psychotic conditions
* Uncontrolled hypertension with systolic blood pressure greater than 180 mmHg
* Myocardial Infarction
* Large vascular aneurysms
* Patients on ketamine as outpatient therapy.

Conditions4

Interventions1

Locations1 site

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