Precision Imaging for Early Detection and Targeted Treatment Monitoring in Pancreatic Cancer

Summary

Specifically, in this project, the objective will be developped a model to capture imaging-based tumor heterogeneity with multiscale radiomics approach by obtaining the mirror tumor image at in vivo MRI, ex vivo MRI at histology. This imaging model giving a perfect virtual histology tumor representation will be secondary implemented on routine in vivo clinical MRI for early cancer detection and treatment monitoring. Successful completion of this proposal will lead to a comprehensive non invasive characterisation of pancreatic cancer and will be a game changer in patient management.

Eligibility

Inclusion Criteria:

* Patient aged \>18 2.
* Pathologically proven pancreatic cancer which can beneficiate of upfront surgery or delayed surgery followed by neoadjuvant chemotherapy.
* Negative pregnancy test for women of childbearing potential
* Patients affiliated to a social protection system
* Written informed consent signed before project onset.

Exclusion Criteria:

* presence of metastases,
* Patient who will not have surgery
* Pregnant or breastfeeding women
* Mental or psychological state, physical or legal incapacity preventing participation in the project.

Conditions2

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