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D-SOLVE Cohorts (Cohort a and B)

RECRUITINGSponsored by Hannover Medical School
Actively Recruiting
SponsorHannover Medical School
Started2023-02-22
Est. completion2026-09-30
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06160635

Summary

Hepatitis D is by far the most severe form of chronic viral hepatitis, frequently leading to liver failure, hepatocellular carcinoma and death. Hepatitis D is caused by coinfection Hepatitis D is caused by co-infection with hepatitis B virus (HBV) and hepatitis D virus (HDV). This multicenter cohort should enable a comprehensive and unbiased biomarker screening of well-defined HDV-infected patients, followed by mechanistic studies to determine the functional role of distinct molecules. Patient surveillance strategies and antiviral treatment approaches could be personalized which should reduce clinical and social disease burden, improve quality of life and save direct and indirect costs caused by HDV infection.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Anti-HDV positive
* ≥18 years old
* Sex: m/f/d
* Informed consent for prospective procedures

Exclusion Criteria:

* Anti-HDV negative

Conditions4

Chronic Liver DiseaseHDVHDV InfectionLiver Disease

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