|

Hormonal Responses to a Mixed Meal in People With Cystic Fibrosis

RECRUITINGEarly 1Sponsored by University of Cincinnati
Actively Recruiting
PhaseEarly 1
SponsorUniversity of Cincinnati
Started2023-03-28
Est. completion2026-07-31
Eligibility
Age18 Years – 45 Years
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT06163482

Summary

In this exploratory study, the hormonal responses to a mixed meal will be examined in people with cystic fibrosis. The aim of this study is to find correlates with impaired glucose tolerance that is associated with this population.

Eligibility

Age: 18 Years – 45 YearsHealthy volunteers accepted
Inclusion Criteria:

* Diagnosed with cystic fibrosis
* Aged 18 to 45 years
* Males and females of any race and ethnicity
* Receiving highly effective CFTR modular therapy

Exclusion Criteria:

* Transplant recipient
* Acute lung function decline or exacerbation within the last 3 months
* Use of systemic glucocorticoids
* Pregnancy
* Known liver disease that would be expected to significantly impact metabolic variable as interpreted by a study doctor
* The presence of any other disease or condition, as interpreted by any one of the study doctors, that would be expected to confound the responses to liquid mixed meal or make participation in the study dangerous to the individual
* People who are cognitively impaired
* People who do not speak English
* For CFRD patients, a daily insulin requirement that exceeds 0.8 U/kg/day
* Any prior history of diabetic ketoacidosis.

Conditions2

Cystic FibrosisDiabetes

Locations1 site

University of Cincinnati
Cincinnati, Ohio, 45267-0547
Jason Winnick, PhD513-558-4437jason.winnick@uc.edu

Browse More Trials

Diabetes trials

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.