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MRE for Assessment of Histopathological Growth Patterns in Colorectal Liver Metastases

RECRUITINGSponsored by Shengjing Hospital
Actively Recruiting
SponsorShengjing Hospital
Started2023-12-24
Est. completion2025-12-24
Eligibility
Age18 Years – 80 Years
Healthy vol.Accepted

Summary

The goal of this study is to investigate the value of MR elastography-based SII as a means of detecting HGP noninvasively in patients with pathology-proven CRLM. MRE will provide a direct measure of tumor-liver adhesion to investigate the relationship between imaging findings and pathophysiological changes in the Liver.

Eligibility

Age: 18 Years – 80 YearsHealthy volunteers accepted
Inclusion Criteria:

* Diagnosed CRLM
* Pathologic results obtained in surgical patients
* No contraindications for magnetic resonance imaging examination

Exclusion Criteria:

* Image quality does not meet the measurement requirements.
* the diameter of CRLM \<1cm
* Combined with other important organ dysfunction
* Combined with malignant tumor
* Patients who do not sign an informed consent
* Patients with metallic implants or foreign bodies in their bodies (pacemakers, artificial metallic heart valves, metal joints, metal implants, and those who cannot remove dentures, insulin pumps, or contraceptive rings)

Conditions4

CancerLiver CancerLiver DiseaseMetastatic Colorectal Cancer

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