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Elastographic Analysis of Urothelial Bladder Tumours

RECRUITINGSponsored by University Hospital, Tours
Actively Recruiting
SponsorUniversity Hospital, Tours
Started2024-02-06
Est. completion2025-02
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

The preoperative evaluation of bladder tumors includes either computed tomography, magnetic resonance imaging in B-mode, or a cystoscopy in the absence of a radiological diagnosis. The diagnosis is confirmed after a transurethral resection of the bladder (TURB) and a histopathological analysis. Ultrasound is a non-invasive imaging technique that uses high-frequency sound waves to produce images of internal structures. Conventional ultrasound in B-mode can only provide details about the tumor's number, size, and location. Elastography uses ultrasound imaging techniques to examine the stiffness of a tissue. Using the Aixplorer system many recently published papers suggested that ShearWave Elasticity (SWE) imaging, enables the differentiation of low- from high-grade breast tumors by assessing the elasticity of the tissue. Investigators intend to evaluate the stiffness of bladder tumors with ultrasound elastography in comparison with cystometry parameters and tumoral grade.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Age \> 18 years
* Bladder tumour visualised on abdominal ultrasound or estimated to be more than 2 cm in diameter by fibroscopy or CT scan
* Primary resection

Exclusion Criteria:

* BMI \> 30 kg/m2,
* Bladder catheterisation,
* Previous bladder or prostate surgery,
* Previous intravesical instillation (BCG / Ametycine)
* Previous pelvic radiotherapy,
* Person having objected to data processing.

Conditions3

CancerElastographic MeasurementIntravesical Pressure Measurement

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