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Maximizing Lymph Node Dissection on Fresh and Fixed Lung Cancer Resection Specimens

RECRUITINGN/ASponsored by Brigham and Women's Hospital
Actively Recruiting
PhaseN/A
SponsorBrigham and Women's Hospital
Started2024-07-26
Est. completion2026-01
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site

Summary

Lung cancer patients undergoing upfront surgery, highly benefit from a systematic lymph node dissection in the mediastinum and in the surgical specimens. The latter is performed by the pathologist. Developing a standardized technique to dissect the lobectomy specimen has the potential of maximizing the retrieval of all N1 stations lymph nodes. The investigators believe that the adoption of such technique will improve lung cancer staging and identify a higher number of patients that qualify for adjuvant therapies.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

1. Subjects with a lung nodule or mass who are eligible to undergo a lobectomy.
2. Subject without any metastasis present.
3. Subjects who have peripheral lung nodule location
4. Subjects must be 18 years of age or older.

Exclusion Criteria:

1. Subjects who received preoperative chemotherapy or radiotherapy.
2. Subjects who have a lung nodule located in a central location. Central tumors are defined by those infiltrating the lobar airway.

Conditions4

CancerLung CancerLymph Node MetastasisPathologic Processes

Locations1 site

Brigham and Womens Hospital
Boston, Massachusetts, 02115
Paula Ugalde Figueroa THORACIC SURGEON, MD6177946491pugaldefigueroa@bwh.harvard.edu

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