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Optimization of Radiation Protection Through Genomic Analyses

RECRUITINGN/ASponsored by University Hospital, Essen
Actively Recruiting
PhaseN/A
SponsorUniversity Hospital, Essen
Started2024-06-01
Est. completion2025-12-15
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06253338

Summary

The long-term goal is to define "signatures" in the form of genomic changes through sequence analyses of genomic DNA using modern Next Generation Sequencing (NGS) methods, which 1. determine the radiation exposure of humans. 2. provide information about the exposure (dose). 3. determine the radiation quality. 4. predict the repair capacity and radiation resistance of an individual.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

ECOG 0/1 no prior treatment no prior cancer diagnosis thoracic or head and neck cancer

Exclusion Criteria:

prior treatment (chemotherapy, radiotherapy, etc.) prior cancer diagnosis

Conditions3

CancerDNARadiation

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