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Establishment of Human Lung Stem Cell Proliferation System and Organoid Construction in COPD

RECRUITINGSponsored by China-Japan Friendship Hospital
Actively Recruiting
SponsorChina-Japan Friendship Hospital
Started2024-03-20
Est. completion2025-12-31
Eligibility
Age18 Years – 55 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06275230

Summary

The goal of this study is to proliferate human lung stem cell in vitro in order to establish a lung organoid derived from patients with COPD. The main question it aims to answer are: * Can human lung stem cell proliferate in vitro. * Can a lung organoid derived from patients with COPD be established. Participants will be sampled during pulmonary bronchoscope for organoid establishment.

Eligibility

Age: 18 Years – 55 YearsHealthy volunteers accepted
Inclusion Criteria:

* 1\. Age under 55, regardless of gender
* 2\. Patients with COPD lung disease who are going to undergo bronchoscopic biopsy
* 3\. No genetic diseases and other respiratory diseases

Exclusion Criteria:

* Other conditions determined by the investigators to be unsuitable for inclusion, such as difficult sampling, difficult follow-up, and complicated with other serious diseases

Conditions2

COPDChronic Obstructive Pulmonary Disease

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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