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Efficacy of Olanzapine on Weight Gain in Advanced Gynecologic Cancer with Paclitaxel and Carboplatin: a Double Blind, Placebo-controlled Randomized Trial

RECRUITINGN/ASponsored by Department of Medical Services Ministry of Public Health of Thailand
Actively Recruiting
PhaseN/A
SponsorDepartment of Medical Services Ministry of Public Health of Thailand
Started2024-04-03
Est. completion2025-03-31
Eligibility
Age18 Years – 70 Years
SexFEMALE
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06288854

Summary

* Efficacy of olanzapine on weight gain in advanced stage gynecologic cancer * Proprotion of pateints in advanced stage gynecologic cancer who recieving paclitaxel and carboplatin chemotherapy gain weight on olanzapine or placebo

Eligibility

Age: 18 Years – 70 YearsSex: FEMALEHealthy volunteers accepted
Inclusion Criteria:

* Advanced stage gynecologic cancer receiving Paclitaxel and carboplatin chemotherapy
* ECOG 0-1
* Normal CBC,Liver, renal function
* Communication in Thai language or Thai caregiver
* Inform consent

Exclusion Criteria:

* Pregnancy
* Active infection
* Bowel obstruction or history of bowel surgery
* On dopamine receptor antagonists or psychiatric or anticonvulsant medication
* Olanzapine allery
* Abnormal function of liver and renal
* Diabetic melitus or morbid obesity
* patient can't selfcare

Conditions2

CancerWeight Gain

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