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Heavy Strength Training in Head and Neck Cancer Survivors

RECRUITINGPhase 2Sponsored by University of Alberta
Actively Recruiting
PhasePhase 2
SponsorUniversity of Alberta
Started2025-02-17
Est. completion2026-06
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

Despite improvements in treatments, head and neck cancer survivors (HNCS) still endure acute and chronic side effects such as loss of muscular strength, limitations in physical functioning, fatigue, and swallowing difficulties that impact quality of life (QoL) and limit return to work. Light-to-moderate intensity strength training (LMST) has been shown to improve some side effects. Heavy lifting strength training (HLST) may further improve outcomes in some populations, however, only one small pilot study has focused on HNCS. The LIFTING 2 trial will be the first to examine the feasibility and effects of a HLST program versus no exercise in HNCS.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* males and females, 18 years of age and older
* any head and neck cancer subtype, stage, and treatment type
* at least 1-year posttreatment with adequate shoulder range of motion (must meet minimum cutpoints for active flexion and abduction to be eligible)
* no unmanaged medical conditions, alcohol, or drug abuse
* approved for exercise by oncologist and a certified exercise physiologist or kinesiologist
* ability to understand and communicate in English

Exclusion Criteria:

* has met the Canadian Physical Activity strength training guidelines within the past one-month: at least two days per week of muscle and bone strength training activities using major muscle groups
* currently involved in a different exercise trial or clinical drug trial

Conditions5

CancerHead and Neck CancerHead and Neck CarcinomaHead and Neck NeoplasmsHead and Neck Squamous Cell Carcinoma

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