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Effect of Continuing Versus Holding Metformin During Hospitalizations.

RECRUITINGPhase 4Sponsored by University of Illinois at Chicago
Actively Recruiting
PhasePhase 4
SponsorUniversity of Illinois at Chicago
Started2025-01-21
Est. completion2026-03-31
Eligibility
Age18 Years – 110 Years
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT06296836

Summary

A randomized study of continuing versus holding metformin during hospitalizations to internal medicine services to determine the effects on glucose control, acidosis, abdominal symptoms, length of stay, and mortality.

Eligibility

Age: 18 Years – 110 YearsHealthy volunteers accepted
Inclusion Criteria:

* Adult (18+ years of age)
* Admitted to an internal medicine service.
* On Metformin prior to admission.

Exclusion Criteria:

* Inability to take oral medications
* eGFR \< 30 ml/min/1.73 m2
* Dialysis
* Current Acidosis (pH \< 7.35) including diabetic ketoacidosis
* Child-Turcotte-Pugh class C hepatic cirrhosis
* Acute Decompensated Heart Failure
* Cognitively impaired and/or unable to consent
* Lack of or unwillingness to share contact information
* Pregnant women

Conditions2

DiabetesDiabetes Mellitus, Type 2

Locations1 site

University of Illinois at Chicago
Chicago, Illinois, 60612
Mathew M Thambi, PharmD, MPHmthambi@uic.edu

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