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Effects of Remote Ischaemic Preconditioning in Cemented Hip Arthroplasty.

RECRUITINGN/ASponsored by University of Tartu
Actively Recruiting
PhaseN/A
SponsorUniversity of Tartu
Started2024-03-20
Est. completion2026-03
Eligibility
Age65 Years – 90 Years
Healthy vol.Accepted

Summary

Total joint arthroplasty is one of the best treatment options for end-stage osteoarthritis. Cemented hip arthroplasty is mainly indicated for elderly patients with poor bone quality and multiple comorbidities. Bone cement implantation syndrome is associated with cemented hip arthroplasty and it has been shown to increase cardiovascular and renal complication and brain damage postoperatively. The aim of this project is to elucidate whether remote-ischemic preconditioning (RIPC) has multi-organ protective effect in cemented hip arthroplasty patients.

Eligibility

Age: 65 Years – 90 YearsHealthy volunteers accepted
Inclusion Criteria:

* age \>65 years
* undergoing total hip cemented hip arthroplasty

Exclusion Criteria:

* previously diagnosed peripheral artery disease on both upper limb
* RIPC is contraindicated

Conditions5

ArthritisBone Cement Implantation SyndromeCardiovascular DiseasesKidney DiseasesOsteoarthritis, Hip

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