Comparison of Free-breathing 3D Quantitative Perfusion in Patients With MINOCA and MINOCA-mimics
NCT06323811
Summary
This clinical study examines patients presenting with acute myocardial infarction and no significant coronary artery disease on coronary angiography (MINOCA) and patients with MINOCA-mimics with advanced CMR. The present study aims to: * assess the microvascular function with a novel quantitative 3D myocardial perfusion imaging approach in the acute phase and post-convalescence * refine the role and diagnostic potential of advanced quantitative CMR imaging * assess the potential prognostic significance of microvascular dysfunction and epicardial adipose tissue on cardiovascular outcomes Participants will undergo advanced CMR imaging in the acute setting (within 10 days after event) and post convalescence (after 3 months).
Eligibility
Inclusion Criteria: * acute presentation with signs/symptoms of acute coronary syndrome or myocarditis * elevated cardiac biomarkers * no signficant coronary artery disease on coronary angiogram or coronary CT Exclusion Criteria: * pacemaker/other devices or claustrophobia * severe asthma, chronic obstructive lung or kidney disease * acute pulmonary embolism * arrhythmia on ECG * moderate to severe valvular disease
Conditions6
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NCT06323811