Reoperative Sentinel Lymph Node Biopsy in Patients With Recurrent Ipsilateral Breast Cancer

Summary

The goal of this observational study is to assess the effectiveness of sentinel lymph node biopsy as a treatment approach for patients with recurrent breast cancer on the same side as previous surgeries. The main questions it aims to answer are: * What is the rate of identification of the sentinel lymph node, and how does it vary among patients with different histories of axillary surgeries? * How can we describe and understand the drainage pathways, including those from the armpit on the same side as the cancer, the area near the breastbone, and the opposite armpit? Participants will undergo sentinel lymph node biopsy as part of their treatment for recurrent breast cancer. They will also receive standard treatments, including surgery and adjuvant therapies as recommended by their healthcare team.

Eligibility

Inclusion Criteria:

* Patients \>18 years old with ipsilateral local recurrence of breast cancer with clinical stage cT1-3 cN0 confirmed by histology, with a history of previous axillary surgery (both sentinel lymph node biopsy and lymphadenectomy).

Exclusion Criteria:

* Patients with confirmed axillary metastasis (histology/immunohistochemistry)
* Inflammatory carcinoma
* Patients with suspected or confirmed distant metastasis on staging studies
* Inability to perform the sentinel lymph node biopsy technique: allergy to radiotracer, mobility limitation

Conditions3

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