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The Role of Oxytocin in Regulating Blood Glucose

RECRUITINGN/ASponsored by University Hospital, Gentofte, Copenhagen
Actively Recruiting
PhaseN/A
SponsorUniversity Hospital, Gentofte, Copenhagen
Started2024-01-01
Est. completion2026-12-31
Eligibility
Age20 Years – 50 Years
SexMALE
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT06334172

Summary

Investigating the effect of oxytocin on pancreatic endocrine functions by determining insulin and glucagon secretion within physiological ranges of plasma glucose.

Eligibility

Age: 20 Years – 50 YearsSex: MALEHealthy volunteers accepted
Inclusion Criteria:

* BMI 19-25 kg/m2

Exclusion Criteria:

* Diabetes
* Heart-, liver or kidney disease
* More than 14 units of alcohol weekly, or drug abuse
* Smoking or any kind of nicotine products
* Alanin aminotransferase (ALAT) ≥ 2 × normal range
* Estimated glomerular filtration rate (eGFR) \< 60 ml/min/1,73m2 or creatinine above normal range
* Blood pressure \> 140/90
* Hemoglobin \< normal range
* Corrected QT Interval (Qtc) \>0,45 sec. at electrocardiogram (ECG) at screening
* Known disease in the pituitary gland or previous pituitary surgery
* Any other disease/condition which the trial managers believe may affect participation in the trial

Conditions2

DiabetesGlucose Metabolism Disorders (Including Diabetes Mellitus)

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