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Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology
RECRUITINGPhase 2/3Sponsored by M.D. Anderson Cancer Center
Actively Recruiting
PhasePhase 2/3
SponsorM.D. Anderson Cancer Center
Started2024-06-11
Est. completion2030-03-31
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →
NCT06336642
Summary
To learn about the effect of Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology (SPOT-ON) treatment on the severity of shortness of breath in patients with cancer.
Eligibility
Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria: * Diagnosis of advanced cancer (metastatic, locally advanced, recurrent, or incurable). * Age 18 or older. * Admitted to a medical floor. * Dyspnea intensity at rest of at least 4 on a 0-10-point NRS (where 0 = none, 10 = worst). * Speak English or Spanish. Exclusion Criteria: * Hemodynamic instability requiring active Merit Team or ICU team involvement. * Delirium as per clinical team's assessment in the Electronic Health Record (EHR). * Severe hypoxemia (SpO2 \< 90% despite supplemental oxygen of up to 6 L/min). * Continuous positive airway pressure (CPAP) use for obstructive sleep apnea, actively using \>10 hours a day. * Respiratory failure necessitating mechanical ventilation (i.e., HFNC or NIV), and planned thoracentesis within 72 hours of enrollment. * Patients with known pregnancy.
Conditions2
CancerDyspnea
Locations1 site
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Actively Recruiting
PhasePhase 2/3
SponsorM.D. Anderson Cancer Center
Started2024-06-11
Est. completion2030-03-31
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →
NCT06336642