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The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury

RECRUITINGN/ASponsored by Sisli Hamidiye Etfal Training and Research Hospital
Actively Recruiting
PhaseN/A
SponsorSisli Hamidiye Etfal Training and Research Hospital
Started2024-04-05
Est. completion2024-08-05
Eligibility
Age65 Years+
Healthy vol.Accepted

Summary

In this prospective, randomized, single-blind study, we aim to compare the effects of general anesthesia and spinal anesthesia on postoperative myocardial injury in elderly patients undergoing hip surgery. Cardiovascular events are a leading cause of mortality and morbidity following non-cardiac surgery, with myocardial injury after non-cardiac surgery (MINS) being a significant concern. MINS, characterized by asymptomatic elevation of troponin levels without accompanying ECG findings, is closely associated with postoperative mortality. With the increasing prevalence of comorbidities in the elderly population and the rising frequency of non-cardiac surgeries in this demographic, understanding the effects of different anesthesia types on postoperative myocardial injury is crucial.

Eligibility

Age: 65 Years+Healthy volunteers accepted
Inclusion Criteria:

* who will undergo hip surgery
* ASAII-III
* Over the age of 65

Exclusion Criteria:

* Patients diagnosed with sepsis, pulmonary embolism, decompensated heart failure, chronic kidney failure.
* Patients who underwent cardioversion in the last 6 months or experienced myocardial infarction.
* Patients with a surgical history in the last month.
* Patients who required intubation in the intensive care unit.
* Patients with a baseline Hs-Troponin T value exceeding 20 ng/L.
* Patients with a postoperative peak Hs-Troponin T value higher than baseline.

Conditions5

Anesthesia, GeneralAnesthesia, SpinalHeart DiseaseHypotension During SurgeryMyocardial Injury After Non-Cardiac Surgery

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